abstract：:The variability of the Apple stem pitting virus (ASPV) coat protein (CP) gene was investigated. The CP gene of ten virus isolates from apple and pear trees was sequenced. Comparison of all sequenced virus isolates revealed high diversity of the CP gene (70.7-93.5% at the nucleotide level and 77.8-98.7% at the amino ac...

journal_title：Virus research

authors： Komorowska B,Siedlecki P,Kaczanowski S,Hasiów-Jaroszewska B,Malinowski T

更新日期：2011-06-01 00:00:00

abstract：:The full-length genomes of 11 infectious bronchitis virus (IBV) field isolates from three different types of the virus; Massachusetts (Mass), Connecticut (Conn) and California (CAL) isolated over a 41, 25 and 8 year period respectively, were sequenced and analyzed to determine the mutation rates and level of polymorph...

journal_title：Virus research

authors： McKinley ET,Jackwood MW,Hilt DA,Kissinger JC,Robertson JS,Lemke C,Paterson AH

更新日期：2011-06-01 00:00:00

abstract：:We previously prepared neutralizing monoclonal antibody (MAb)-resistant (mar) mutant viruses using a laboratory strain feline infectious peritonitis virus (FIPV) 79-1146 (Kida et al., 1999). Mar mutant viruses are mutated several amino acids of the neutralizing epitope of Spike protein, compared with the parent strain...

journal_title：Virus research

authors： Takano T,Tomiyama Y,Katoh Y,Nakamura M,Satoh R,Hohdatsu T

更新日期：2011-03-01 00:00:00

abstract：:Application of bacteriophages and their lytic enzymes to control Clostridium perfringens is one potential approach to reduce the pathogen on poultry farms and in poultry-processing facilities. Bacteriophages lytic for C. perfringens were isolated from sewage, feces and broiler intestinal contents and ΦCPV1, a virulent...

journal_title：Virus research

authors： Volozhantsev NV,Verevkin VV,Bannov VA,Krasilnikova VM,Myakinina VP,Zhilenkov EL,Svetoch EA,Stern NJ,Oakley BB,Seal BS

更新日期：2011-02-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) is characteristic of genetically extensive variation. In this study, five SPF pigs were co-infected with two strains of PRRSV (JXwn06-81c and HB-1/3.9c), and 352 viruses were cloned by plaque assay from the sera of the infected pigs on days 3, 5, 7, 10, 14, 2...

journal_title：Virus research

authors： Liu D,Zhou R,Zhang J,Zhou L,Jiang Q,Guo X,Ge X,Yang H

更新日期：2011-02-01 00:00:00

abstract：:Equine rhinitis B virus (ERBV) is the single species in the genus Erbovirus, family Picornaviridae. Equine rhinitis B viruses exist in three serotypes and are associated with respiratory disease in horses. Members of the species vary in stability at acid pH. To date there has been discordance in genotype, serotype and...

journal_title：Virus research

authors： Horsington JJ,Gilkerson JR,Hartley CA

更新日期：2011-02-01 00:00:00

abstract：:Subtype C is the most prevalent HIV-1 subtype globally and a common circulating recombinant form virus, CRF_BC, is predominant in China. It is unclear whether subtype C-based vaccines are capable of neutralizing CRF_BC viruses or can be evaluated using a neutralization assay based on CRF_BC pseudoviruses. Phylogenetic...

journal_title：Virus research

authors： Wang S,Nie J,Wang Y

更新日期：2011-01-01 00:00:00

abstract：:There are over 350 million people chronically infected with the Hepatitis B virus (HBV); chronic HBV infections are associated with the development of hepatocellular carcinoma (HCC). While the precise mechanism of HBV-associated HCC remains undefined, it is believed to involve a combination of the host immune response...

journal_title：Virus research

authors： Gearhart TL,Bouchard MJ

更新日期：2011-01-01 00:00:00

abstract：:The structural envelope glycoprotein GP4 of European porcine reproductive and respiratory syndrome virus (PRRSV) strains contains a highly variable neutralizing epitope that is susceptible to neutralizing antibody-mediated selective pressure in vitro. In this study, it was analyzed what happens with this neutralizing ...

journal_title：Virus research

authors： Costers S,Vanhee M,Van Breedam W,Van Doorsselaere J,Geldhof M,Nauwynck HJ

更新日期：2010-12-01 00:00:00

abstract：:Prior studies on PRRSV strain VR-2332 non-structural protein 2 (nsp2) had shown that as much as 403 amino acids could be removed from the hypervariable region without losing virus viability in vitro. We utilized selected nsp2 deletion mutants to examine in vivo growth. Young swine (4 pigs/group; 5 control swine) were ...

journal_title：Virus research

authors： Faaberg KS,Kehrli ME Jr,Lager KM,Guo B,Han J

更新日期：2010-12-01 00:00:00

abstract：:Marek's disease virus (MDV) is an oncogenic herpesvirus that causes a disease in chickens characterized by tumor formation and immunosuppression. In this paper, we identified differentially expressed proteins in the bursa of Fabricius of chickens infected with the highly virulent MDV strain RB1B, using two-dimensional...

journal_title：Virus research

authors： Lu Z,Qin A,Qian K,Chen X,Jin W,Zhu Y,Eltahir YM

更新日期：2010-11-01 00:00:00

abstract：:The generation of a new panel of 32 monoclonal antibodies (MAbs) reactive with the P protein of the raccoon strain of rabies virus is described. Through a series of analyses employing competitive ELISA and immunoblotting, these MAbs were classified into eight groups, each defining an antigenic site, thereby increasing...

journal_title：Virus research

authors： Nadin-Davis SA,Fehlner-Gardiner C,Sheen M,Wandeler AI

更新日期：2010-09-01 00:00:00

abstract：:An orange stem pitting citrus tristeza virus (CTV) isolate CTV-B165 was found to be symptomatically similar to other known CTV-VT isolates however molecular methods failed to classify it as an identifiable CTV genotype. The sequence variation of the Indian CTV-B165 isolate was compared to the three well known CTV geno...

journal_title：Virus research

authors： Roy A,Brlansky RH

更新日期：2010-08-01 00:00:00

abstract：:Infectious salmon anaemia virus (ISAV) is a piscine orthomyxovirus causing a serious disease in farmed Atlantic salmon (Salmo salar L.). The virus surface glycoprotein hemagglutinin-esterase (HE) is responsible for both viral attachment and release. Similarity to bovine and porcine torovirus hemagglutinin-esterase (BT...

journal_title：Virus research

authors： Müller A,Markussen T,Drabløs F,Gjøen T,Jørgensen TØ,Solem ST,Mjaaland S

更新日期：2010-08-01 00:00:00

abstract：:Typically plasma viremia is controlled in macaques challenged with R5 tropic SHIV162P3 during the chronic phase of infection. However, in a few infected animals it sustains for a prolonged period. Persistent plasma viremia in two such macaques led to a rapid decline of CD4+ T-cells in blood leading to the induction of...

journal_title：Virus research

authors： Chung HK,Suschak J,Galmin L,Rose N,Pal R

更新日期：2010-08-01 00:00:00

abstract：:Heparan sulfate moieties of cell surface proteoglycans serve as receptors for several herpesviruses. For herpes simplex virus 1, pseudorabies virus and equine herpesvirus 1, glycoprotein C (gC) homologues have been shown to mediate the binding to cell surface heparan sulfate. However, the role of gC in equine herpesvi...

journal_title：Virus research

authors： Azab W,Tsujimura K,Maeda K,Kobayashi K,Mohamed YM,Kato K,Matsumura T,Akashi H

更新日期：2010-07-01 00:00:00

abstract：:Papillomaviruses infect keratinocytes and their reproduction is tied to differentiation of the skin. The E2 protein of papillomaviruses is a multifunctional early protein that binds specifically to the viral DNA to regulate genome transcription, replication, and segregation. All of these are nuclear events that requir...

journal_title：Virus research

authors： Bian XL,Wilson VG

更新日期：2010-06-01 00:00:00

abstract：:The nucleocapsids formation is a pivotal step of hepatitis B virus (HBV) life cycle. The inhibition of HBV nucleocapsids assembly is a promising strategy for the anti-HBV treatment. HBc78-117 is an internal fragment of hepatitis B core protein (HBc). In this study, we used lentiviral vector to deliver HBc78-117 cDNA s...

journal_title：Virus research

authors： Han J,Pan X,Gao Y,Weil L

更新日期：2010-06-01 00:00:00

abstract：:Porcine epidemic diarrhea virus (PEDV) has plagued the domestic swine industry in Korea causing significant economic impacts on pig production nationwide. In the present study, we determined the complete nucleotide sequences of the spike (S) glycoprotein genes of seven Korean PEDV isolates. The entire S genes of all i...

journal_title：Virus research

authors： Lee DK,Park CK,Kim SH,Lee C

更新日期：2010-05-01 00:00:00

abstract：:By Western blot analyzes of expression of avian reovirus proteins, one unknown fragment was detected by an anti-sigmaA monoclonal antibody in virus-infected cells lysate. It was interesting to note that RNA interference against sigmaA resulted in the suppression of the unknown fragment. Using various lengths of sigmaA...

journal_title：Virus research

authors： Ji WT,Lin FL,Wang YC,Shih WL,Lee LH,Liu HJ

更新日期：2010-04-01 00:00:00

abstract：:The mechanism by which hepatitis B virus (HBV) infection causes severe inflammatory liver diseases is multifactorial and related to interactions with cell signaling pathways and the ensuing inflammatory response. Activation of JAK/STAT/SOCS signaling is essential for the induction of cellular antiviral responses, cont...

journal_title：Virus research

authors： Koeberlein B,zur Hausen A,Bektas N,Zentgraf H,Chin R,Nguyen LT,Kandolf R,Torresi J,Bock CT

更新日期：2010-03-01 00:00:00

abstract：:Theiler's murine encephalomyelitis virus is divided into two subgroups on the basis of their different biological activities. GDVII subgroup strains cause acute and fatal encephalomyelitis in mice, while TO or DA subgroup strains cause non-fatal polioencephalomyelitis in weanling mice followed by virus persistence and...

journal_title：Virus research

authors： Ichinose-Asakura K,Taniura N,Himeda T,Nojiri M,Okuwa T,Ohara Y

更新日期：2010-02-01 00:00:00

abstract：:We performed phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from 76 children with acute respiratory infection in Yamagata prefecture, Japan during the period 2003-2007. Phylogenetic trees based on the nucleotide and amino acid sequences of the VP4/VP2 coding region showed that the pre...

journal_title：Virus research

authors： Mizuta K,Hirata A,Suto A,Aoki Y,Ahiko T,Itagaki T,Tsukagoshi H,Morita Y,Obuchi M,Akiyama M,Okabe N,Noda M,Tashiro M,Kimura H

更新日期：2010-02-01 00:00:00

abstract：:Analysis of complete polyprotein-encoding sequences of the two most prevalent genotypes of hepatitis C virus (HCV-1a and HCV-1b) revealed evidence of abundant, slightly deleterious nonsynonymous variants subject to ongoing purifying selection. In the case of both HCV-1a and HCV-1b, the NS3 protein demonstrated a high ...

journal_title：Virus research

authors： Irausquin SJ,Hughes AL

更新日期：2010-02-01 00:00:00

abstract：:The spread of H5N1 virus into a wide range of avian and mammalian species may facilitate the adaptation of the virus to human populations. In the present study, a survey of avian influenza virus in tree sparrows was performed and a HPAI H5N1 virus (A/tree sparrow/Jiangsu/1/08) was isolated. The H5N1 virus was found to...

journal_title：Virus research

authors： Liu Q,Ma J,Kou Z,Pu J,Lei F,Li T,Liu J

更新日期：2010-01-01 00:00:00

abstract：:The fidelity of poliovirus RNA-dependent RNA polymerase (3Dpol) was determined using a modified alpha-complementation assay. Several polymerases have been analyzed by this approach allowing comparisons to be drawn. Various conditions including high and low MgCl(2), replacing MgCl(2) with MnCl(2), skewed nucleotide poo...

journal_title：Virus research

authors： DeStefano JJ

更新日期：2010-01-01 00:00:00

abstract：:Transcription of human immunodeficiency virus (HIV-1) is activated by viral Tat protein which regulates HIV-long terminal repeat (LTR) transcription and elongation. HIV-1 Tat protein is a substrate for the deacetylase activity of sirtuin 1 (SIRT1). Here we investigate the signaling pathway involved in Tat-induced HIV-...

journal_title：Virus research

authors： Zhang HS,Wu MR

更新日期：2009-12-01 00:00:00

abstract：:Bovine herpesvirus-1 infected cell protein 27 (BICP27) was detected predominantly in the nucleolus. The open reading frame of BICP27 was fused with the enhanced yellow fluorescent protein (EYFP) gene to investigate its subcellular localization in live cells and BICP27 was able to direct monomeric, dimeric or trimeric ...

journal_title：Virus research

authors： Guo H,Ding Q,Lin F,Pan W,Lin J,Zheng AC

更新日期：2009-11-01 00:00:00

abstract：:The core proteins of epizootic haemorrhagic disease virus (EHDV) have important roles to perform in maintaining the structure and function of the virus. A complete genetic and phylogenetic analysis was therefore performed on these proteins (and the genes that code for them) to allow comparison of the selective pressur...

journal_title：Virus research

authors： Anthony SJ,Maan N,Maan S,Sutton G,Attoui H,Mertens PP

更新日期：2009-11-01 00:00:00

abstract：:Influenza A viruses are characterized by a unique genome structure, causing genetic instability, especially to the genes of haemagglutinin and neuraminidase. The objectives of this research was molecular and phylogenetic analysis of influenza A(H3N2) strains that circulated in Northern Greece since 2004, particularly ...

journal_title：Virus research

authors： Melidou A,Exindari M,Gioula G,Chatzidimitriou D,Pierroutsakos Y,Diza-Mataftsi E

更新日期：2009-11-01 00:00:00

abstract：:Several cell surface molecules have been implicated in rotavirus cell entry, however, their individual relevance during this process is unknown. In this work, the expression of integrins alpha2, beta2, and alpha v beta 3, the heat shock cognate protein 70, and of ganglioside GM1 in different cell lines of human and si...

journal_title：Virus research

authors： Isa P,Sánchez-Alemán MA,López S,Arias CF

更新日期：2009-11-01 00:00:00

abstract：:Although a significant progress has been achieved on dsRNA mediated anti-virus strategy development, there is still no effective means to control the virulent white spot syndrome virus (WSSV). Six double-stranded RNAs specific to different essential genes of WSSV (ie1, ie3, pol (DNA polymerase), rr2 (ribonucleotide re...

journal_title：Virus research

authors： Attasart P,Kaewkhaw R,Chimwai C,Kongphom U,Namramoon O,Panyim S

更新日期：2009-10-01 00:00:00

abstract：:Forty Chinese PCV2 strains collected between 2004 and 2008 were sequenced and their genetic variations were analyzed together with nine previous PCV2 isolates. Phylogenetic analysis indicated that these Chinese PCV2 strains could be divided into four genotypes (PCV-2a, PCV-2b, PCV-2d and PCV-2e), and the genotype PCV-...

journal_title：Virus research

authors： Wang F,Guo X,Ge X,Wang Z,Chen Y,Cha Z,Yang H

更新日期：2009-10-01 00:00:00

abstract：:To investigate the evolutionary origins of proteins encoded by the Poxviridae family of viruses, we examined all poxvirus protein coding genes using a method of characterizing and visualizing the similarity between these proteins and taxonomic subsets of proteins in GenBank. Our analysis divides poxvirus proteins into...

journal_title：Virus research

authors： Odom MR,Hendrickson RC,Lefkowitz EJ

更新日期：2009-09-01 00:00:00

abstract：:Genome organization and gene expression of Borna disease virus (BDV) are remarkable for the overlap of open reading frames, transcription units and transcription signals, readthrough of transcription termination signals, differential use of translation initiation codons, and exploitation of the cellular splicing machi...

journal_title：Virus research

authors： Siemetzki U,Ashok MS,Briese T,Lipkin WI

更新日期：2009-09-01 00:00:00

abstract：:Chronic bee paralysis virus (CBPV) is responsible for chronic paralysis, an infectious and contagious disease of adult honey bees (Apis mellifera L.). The full-length nucleotide sequences of the two major RNAs of CBPV have previously been characterized. The Orf3 of RNA1 has shown significant similarities to the RNA-de...

journal_title：Virus research

authors： Blanchard P,Schurr F,Olivier V,Celle O,Antùnez K,Bakonyi T,Berthoud H,Haubruge E,Higes M,Kasprzak S,Koeglberger H,Kryger P,Thiéry R,Ribière M

更新日期：2009-09-01 00:00:00

abstract：:The biogeographical history of rabies can be reconstructed using molecular data. This work describes the genetic characterization of the Rabies virus variant that circulates in the Desmodus rotundus (vampire bat) population in an epizootic area and is transmitted to herbivorous livestock. The N and G genes of this vir...

journal_title：Virus research

authors： Carnieli P Jr,Castilho JG,Fahl Wde O,Véras NM,Timenetsky Mdo C

更新日期：2009-09-01 00:00:00

abstract：:The full genomic nucleotide sequence of a previously identified genotype 3 hepatitis E virus (HEV), strain SAAS-JDY5, was obtained using RT-PCR and rapid amplification of cDNA ends (RACE). The genome consisted of 7225 nucleotides, excluding a poly-A tail at the 3' terminus, and contained three open reading frames (ORF...

journal_title：Virus research

authors： Si FS,Zhu YM,Dong SJ,Yu SS,Yu RS,Shen SY,Yang Q,Li Z

更新日期：2009-09-01 00:00:00

abstract：:Since wild ducks constitute a vital element in the epizootiology of avian influenza viruses (AIVs) as well as avian paramyxoviruses (APMVs) and play a key role in the ecology and inter-species transmission of these viruses, it is crucial to elucidate the diversity and prevalence of these viruses within these bird popu...

journal_title：Virus research

authors： Jahangir A,Ruenphet S,Ueda S,Ueno Y,Shoham D,Shindo J,Okamura M,Nakamura M,Takehara K

更新日期：2009-07-01 00:00:00

abstract：:Equine rhinitis A virus (ERAV) is a picornavirus which causes an acute respiratory infection in horses worldwide, and virus neutralization (VN) has been the standard method for the detection of ERAV antibody in horse serum. Previous studies have identified recombinant virion protein VP1 (rVP1) purified under native co...

journal_title：Virus research

authors： Kriegshäuser G,Kuechler E,Skern T

更新日期：2009-07-01 00:00:00